Question 1

How might a thermophilic bacterium use chromosome structure to protect against heat-induced DNA degradation?

Accepted Answer

A)  It expresses excess amounts of SMC proteins that allow the DNA to more tightly condense during periods of high heat.
B)  It can express a specialized topoisomerase that induces negative supercoiling,which provides additional chromosomal stability.
C)  It expresses a specialized topoisomerase that induces positive supercoiling,which provides additional chromosomal stability.
D)  It expresses enzymes that inhibit topoisomerase during high heat,which prevents DNA from unwinding and becoming susceptible to heat degradation.
E)  It expresses helicase,an enzyme that nicks the DNA helix and allows it to assume a more stable conformation and thus to resist heat-induced degradation.F) A) and D)
G) C) and D)

Question 2

Given what you know about coat color in cats,list the possible genotypes for these individuals:
• orange male
• orange female
• black male
• black female
• tortoiseshell

Accepted Answer

O⁻,OO,o⁻,o...

Question 3

Nucleosome displacement during transcription initiation is referred to as what?

Accepted Answer

chromatin ...

Question 4

Histone deacetylase (HDAC)inhibitors are commonly used as mood stabilizers or in the treatment of neurodegenerative diseases.What effect would a HDAC inhibitor have on the target cells?

Accepted Answer

A histone deacetylase removes acetyl gro...

Question 5

A bacterium inherits a mutation that renders its topoisomerase enzyme nonfunctional.What phenotype would you expect to see in this bacterium?

Accepted Answer

A)  The cell would accumulate broken DNA because overwinding cannot be corrected,so the cell will be unable to replicate and will die.
B)  The cell would accumulate supercoiled DNA,but otherwise it is perfectly normal.
C)  The cell would accumulate relaxed DNA,which would make DNA replication and cell division highly disorganized and lead to cell death.
D)  The cell would accumulate relaxed DNA,but otherwise it is perfectly normal.
E)  The cell would be unaffected because bacteria have many different topoisomerases that are involved in replication.F) D) and E)
G) C) and E)

Question 6

What molecular interaction allows histones to interact with DNA?

Accepted Answer

positive c...

Question 7

How many pairs of chromosomes are found in a typical human somatic cell's karyotype?

Accepted Answer

A)  0
B)  22
C)  23
D)  44
E)  46F) B) and D)
G) A) and C)

Question 8

If you want to prevent chromatin loops from being anchored to the chromosome scaffold,which regions of the DNA would you target?

Accepted Answer

MARS (matr...

Question 9

You are attempting to isolate cells for your karyotype,and you find one cell in each of the phases (prophase,metaphase,anaphase,and telophase).Which one is best suited for a karyotype?

Accepted Answer

The answer of You are attempting to isolate cells for...

Question 10

What is meant by the "beads on a string" model of chromatin?

Accepted Answer

A)  The beads are the histones,and the string is the transcriptionally active DNA loops.
B)  The beads are the nucleosomes,and the string is the linker DNA.
C)  The beads are molecules of DNA polymerase that attach to the DNA string.
D)  The beads are ribosomes,and the string is the mRNA that has been transcribed from active chromatin.
E)  The beads are the heterochromatic regions that are tightly compacted,and the strings are euchromatic regions that are being actively transcribed.F) All of the above
G) A) and C)

Question 11

Chromosome condensation compacts the chromosomes so they can be efficiently separated at which phase of mitosis?

Accepted Answer

The answer of Chromosome condensation compacts the chromosomes so they...

Exam 11: Chromosome Structure

How might a thermophilic bacterium use chromosome structure to protect against heat-induced DNA degradation?

Correct Answer
verified

Given what you know about coat color in cats,list the possible genotypes for these individuals: • orange male • orange female • black male • black female • tortoiseshell

Correct Answer
verified
O⁻,OO,o⁻,o...
View Answer

Nucleosome displacement during transcription initiation is referred to as what?

Correct Answer
verified
chromatin ...
View Answer

You are attempting to isolate cells for your karyotype,and you find one cell in each of the phases (prophase,metaphase,anaphase,and telophase).Which one is best suited for a karyotype?

Correct Answer
verified

If you want to prevent chromatin loops from being anchored to the chromosome scaffold,which regions of the DNA would you target?

Correct Answer
verified
MARS (matr...
View Answer

How many pairs of chromosomes are found in a typical human somatic cell's karyotype?

Correct Answer
verified

Chromosome condensation compacts the chromosomes so they can be efficiently separated at which phase of mitosis?

Correct Answer
verified

What is meant by the "beads on a string" model of chromatin?

Correct Answer
verified

A bacterium inherits a mutation that renders its topoisomerase enzyme nonfunctional.What phenotype would you expect to see in this bacterium?

Correct Answer
verified

Histone deacetylase (HDAC)inhibitors are commonly used as mood stabilizers or in the treatment of neurodegenerative diseases.What effect would a HDAC inhibitor have on the target cells?

Correct Answer
verified
A histone deacetylase removes acetyl gro...
View Answer

What molecular interaction allows histones to interact with DNA?

Correct Answer
verified
positive c...
View Answer

Exam 11: Chromosome Structure

How might a thermophilic bacterium use chromosome structure to protect against heat-induced DNA degradation?

Correct AnswerverifiedShow Answer

Given what you know about coat color in cats,list the possible genotypes for these individuals: • orange male • orange female • black male • black female • tortoiseshell

Correct AnswerverifiedO⁻,OO,o⁻,o...View AnswerShow Answer

Nucleosome displacement during transcription initiation is referred to as what?

Correct Answerverifiedchromatin ...View AnswerShow Answer

You are attempting to isolate cells for your karyotype,and you find one cell in each of the phases (prophase,metaphase,anaphase,and telophase).Which one is best suited for a karyotype?

Correct AnswerverifiedShow Answer

If you want to prevent chromatin loops from being anchored to the chromosome scaffold,which regions of the DNA would you target?

Correct AnswerverifiedMARS (matr...View AnswerShow Answer

How many pairs of chromosomes are found in a typical human somatic cell's karyotype?

Correct AnswerverifiedShow Answer

Chromosome condensation compacts the chromosomes so they can be efficiently separated at which phase of mitosis?

Correct AnswerverifiedShow Answer

What is meant by the "beads on a string" model of chromatin?

Correct AnswerverifiedShow Answer

A bacterium inherits a mutation that renders its topoisomerase enzyme nonfunctional.What phenotype would you expect to see in this bacterium?

Correct AnswerverifiedShow Answer

Histone deacetylase (HDAC)inhibitors are commonly used as mood stabilizers or in the treatment of neurodegenerative diseases.What effect would a HDAC inhibitor have on the target cells?

Correct AnswerverifiedA histone deacetylase removes acetyl gro...View AnswerShow Answer

What molecular interaction allows histones to interact with DNA?

Correct Answerverifiedpositive c...View AnswerShow Answer

Correct Answer
verified

Correct Answer
verified
O⁻,OO,o⁻,o...
View Answer

Correct Answer
verified
chromatin ...
View Answer

Correct Answer
verified

Correct Answer
verified
MARS (matr...
View Answer

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified
A histone deacetylase removes acetyl gro...
View Answer

Correct Answer
verified
positive c...
View Answer