Question 1

A reversal of the normal serum albumin/globulin (A/G) ratio occurs in ____ disease.

Accepted Answer

A)   heart and lung
B)   kidney and bone
C)   heart and liver
D)   kidney and liverE) All of the above
F) A) and C)

Question 2

Match the name of the tumor specific marker assay with an appropriate application.
-CEA

Accepted Answer

A)  suggests early recurrence of breast cancer
B)  secreted in endodermal sinus tumors
C)  detected in choriocarcinoma
D)  found in 20% of smokersE) A) and B)
F) None of the above

Question 3

It is important to record the exact time and date in relation to the last dose of the drug when drawing a blood specimen for therapeutic drug monitoring.

Accepted Answer

A) True 
 B)False

Question 4

Match the following terms with the correct description. Use an answer only once.
-respiratory acidosis

Accepted Answer

A)  decreased plasma bicarbonate
B)  excess elimination of acid
C)  acid-rich fluids are lost
D)  decreased elimination of CO₂E) A) and C)
F) A) and B)

Question 5

An increased anion gap may be due to:

Accepted Answer

A)   lactic acidosis.
B)   hypercalcemia.
C)   hypermagnesemia.
D)   hypoproteinemia.E) B) and D)
F) B) and C)

Question 6

Laboratory diagnosis of an acute myocardial infarction (MI) is most accurately determined with which of the following two cardiac markers?

Accepted Answer

A)   CK-MB and homocysteine
B)   CRP (C-reactive protein)  and cardiac troponin
C)   Myoglobin and lactate dehydrogenase (LDH) 
D)   Myoglobin and cardiac troponinE) All of the above
F) A) and B) D

Question 7

Which of the following enzymes is normally found in highest levels in hepatocytes,or liver cells?

Accepted Answer

A)   ALT
B)   AST
C)   GGT
D)   Alkaline phosphataseE) B) and D)
F) All of the above

Question 8

Fasting lipid profile results for a 48-year-old male with diabetes are as follows: total cholesterol: 298 mg/dL,HDL cholesterol: 26 mg/dL,and triglycerides: 320 mg/dL.The patient has no evidence of coronary artery disease (CAD) .What is the recommended course of action?

Accepted Answer

A)   The LDL is normal, and no action is indicated.
B)   The LDL is elevated, and the therapeutic goal is to decrease it to less than 100 mg/dL.
C)   The LDL is elevated, and the therapeutic goal is to decrease it to less than 130 mg/dL.
D)   The LDL is elevated, and the therapeutic goal is to decrease it to less than 160 mg/dL.E) C) and D)
F) A) and C)

Question 9

An adult male has a serum BUN of 56 mg/dL and a creatinine of 0.8 mg/dL.These results are consistent with:

Accepted Answer

A)   decreased GFR.
B)   prerenal azotemia.
C)   renal azotemia.
D)   postrenal azotemia.E) B) and C)
F) A) and C)

Question 10

The adult reference range for fasting serum glucose is ____ mg/dL.

Accepted Answer

A)   40-75
B)   55-105
C)   60-95
D)   70-110E) B) and C)
F) None of the above

Question 11

Match the following terms with the correct description. Use an answer only once.
-respiratory alkalosis

Accepted Answer

A)  decreased plasma bicarbonate
B)  excess elimination of acid
C)  acid-rich fluids are lost
D)  decreased elimination of CO₂E) A) and B)
F) B) and C)

Question 12

Which of the following conditions is least likely to contribute to an increased serum uric acid level?

Accepted Answer

A)   Chemotherapy
B)   Renal disease
C)   Liver disease
D)   GoutE) B) and C)
F) B) and D) C

Question 13

The term for the condition associated with elevated serum potassium is:

Accepted Answer

A)   hyponatremia.
B)   hypernatremia.
C)   hypokalemia.
D)   hyperkalemia.E) A) and B)
F) A) and C)

Question 14

Free T₄ is ____ and thyroid stimulating hormone is ____ in hypothyroidism.

Accepted Answer

A)   increased; decreased
B)   decreased; increasedC) A) and B)
D) undefined

Question 15

Match the name of the tumor specific marker assay with an appropriate application.
-CA 27.29

Accepted Answer

A)  suggests early recurrence of breast cancer
B)  secreted in endodermal sinus tumors
C)  detected in choriocarcinoma
D)  found in 20% of smokersE) A) and B)
F) None of the above A

Question 16

Estimation of the blood glucose level over the previous 4 to 6 weeks is determined with which test?

Accepted Answer

A)   HbA1c
B)   Ketones
C)   Clinitest
D)   MicroalbuminE) A) and B)
F) B) and C)

Question 17

The first step in the laboratory determination of serum cholesterol is to ensure that all cholesterol present is in the free form.This is accomplished with the use of:

Accepted Answer

A)   cholesterol esterase.
B)   glycerol.
C)   cholesterol oxidase.
D)   lipase.E) B) and C)
F) None of the above

Question 18

Match the name of the tumor specific marker assay with an appropriate application.
- β\betaβ -hCG

Accepted Answer

A)  suggests early recurrence of breast cancer
B)  secreted in endodermal sinus tumors
C)  detected in choriocarcinoma
D)  found in 20% of smokers E) None of the above
F) A) and B)

Question 19

Contributory factors to which form of diabetes include a genetic predisposition and autoimmune destruction of pancreatic b cells?

Accepted Answer

A)   Type 1
B)   Type 2
C)   Gestational diabetes mellitus
D)   Stress-induced hyperglycemiaE) B) and C)
F) All of the above

Question 20

Which of the following is the least utilized role of a tumor marker?

Accepted Answer

A)   Cancer screening
B)   Cancer diagnosis
C)   Monitoring of patients for a recurrence of cancer
D)   Determination of the extent of tumor burdenE) A) and D)
F) A) and C)

Exam 10: Introduction to Clinical Chemistry

A reversal of the normal serum albumin/globulin (A/G) ratio occurs in ____ disease.

Correct AnswerverifiedShow Answer

Match the name of the tumor specific marker assay with an appropriate application. -CEA

Correct AnswerverifiedShow Answer

It is important to record the exact time and date in relation to the last dose of the drug when drawing a blood specimen for therapeutic drug monitoring.

Correct AnswerverifiedShow Answer

Match the following terms with the correct description. Use an answer only once. -respiratory acidosis

Correct AnswerverifiedShow Answer

An increased anion gap may be due to:

Correct AnswerverifiedShow Answer

Laboratory diagnosis of an acute myocardial infarction (MI) is most accurately determined with which of the following two cardiac markers?

Correct AnswerverifiedD

Which of the following enzymes is normally found in highest levels in hepatocytes,or liver cells?

Correct AnswerverifiedShow Answer

Fasting lipid profile results for a 48-year-old male with diabetes are as follows: total cholesterol: 298 mg/dL,HDL cholesterol: 26 mg/dL,and triglycerides: 320 mg/dL.The patient has no evidence of coronary artery disease (CAD) .What is the recommended course of action?

Correct AnswerverifiedShow Answer

An adult male has a serum BUN of 56 mg/dL and a creatinine of 0.8 mg/dL.These results are consistent with:

Correct AnswerverifiedShow Answer

The adult reference range for fasting serum glucose is ____ mg/dL.

Correct AnswerverifiedShow Answer

Match the following terms with the correct description. Use an answer only once. -respiratory alkalosis

Correct AnswerverifiedShow Answer

Which of the following conditions is least likely to contribute to an increased serum uric acid level?

Correct AnswerverifiedC

The term for the condition associated with elevated serum potassium is:

Correct AnswerverifiedShow Answer

Free T₄ is ____ and thyroid stimulating hormone is ____ in hypothyroidism.

Correct AnswerverifiedShow Answer

Match the name of the tumor specific marker assay with an appropriate application. -CA 27.29

Correct AnswerverifiedA

Estimation of the blood glucose level over the previous 4 to 6 weeks is determined with which test?

Correct AnswerverifiedShow Answer

The first step in the laboratory determination of serum cholesterol is to ensure that all cholesterol present is in the free form.This is accomplished with the use of:

Correct AnswerverifiedShow Answer

Match the name of the tumor specific marker assay with an appropriate application. - β\betaβ -hCG

Correct AnswerverifiedShow Answer

Contributory factors to which form of diabetes include a genetic predisposition and autoimmune destruction of pancreatic b cells?

Correct AnswerverifiedShow Answer

Which of the following is the least utilized role of a tumor marker?

Correct AnswerverifiedShow Answer

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D

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C

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Free T₄ is and thyroid stimulating hormone is in hypothyroidism.

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A

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Match the name of the tumor specific marker assay with an appropriate application. - $\beta$ -hCG

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